Changes in the brain Met-enkephalin, Leu-enkephalin and dynorphin concentrations in stressful situations
نویسندگان
چکیده
منابع مشابه
Immunocytochemical and ultrastructural differentiation between Met-enkephalin-, Leu-enkephalin-, and Met/Leu-enkephalin-immunoreactive neurons of feline gut.
Selective immunocytochemical procedures, applied at the light and electron microscopical level, have resulted in the identification of three types of enkephalin-immunoreactive nerves in the feline gastrointestinal tract, including neurons containing either Met- or Leu-enkephalin immunoreactivity or those simultaneously storing both Met- and Leu-enkephalin immunoreactants. The three different ty...
متن کاملProbable precursors of [Leu]enkephalin and [Met]enkephalin in adrenal medulla: peptides of 3-5 kilodaltons.
Adrenal chromaffin granules contain at least 10 peptides, ranging in size from 3 to 5 kilodaltons, that yield, upon digestion with trypsin, peptides that show specific binding to opiate receptors. All are distinctly different from beta-endorphin. Two of these peptides have been purified to homogeneity and subjected to chemical analysis. One is apparently a [Met]enkephalin precursor containing t...
متن کاملLeu-enkephalin purification from E. coli cells carrying the plasmid with fused synthetic leu-enkephalin gene.
Chemically synthesized leu-enkephalin gene was fused to a large Eco RI-Bam HI fragment of pBR322 along with a Eco RI fragment of Ch4A phage DNA carrying the promoter and most of the E.coli beta-galactosidase gene. The resulting recombinant DNA was used to transform E. coli cells. Transformants were screened for Tc-sensitivity, Am-resistance, and beta-galactosidase constitutional synthesis. Rest...
متن کاملImmunohistochemical studies on the gastrointestinal tract using antisera to Met-enkephalin and Met-enkephalin Arg6Phe7.
Antisera specific for the C-terminus of Met-enkephalin and two of its variants isolated from adrenal medulla and brain, namely Met-enk Arg6 and Met-enk Arg6Phe7, have been used in immunohistochemical studies of the gastrointestinal tract in rat, mouse and guinea pig. Met-enk and Met-enk Arg6Phe7-like immunoreactivities were found with similar distribution in nerve cell bodies of the myenteric p...
متن کاملImmunocytochemical studies with antisera against leu-enkephalin and an enkephalin-precursor fragment (BAM-22P) in the rat brain.
Rats given high doses of colchicine (300-400 ug, i.c.v.) were used to investigate the comparative distribution of Leu-enkephalin and bovine adrenal medullary enkephalinprecursor fragment (BAM-22P) in the brain. Leu-enkephalin immunoreactive neurons have a widespread distribution throughout the neuraxis. In most areas adjacent section analysis showed BAM-22P and Leu-enkephalin immunoreactive per...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1990
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)55131-9